MGRG

News

In July 2020, Dr. Taylor was awarded an NSF Campus Cyberinfrastructure grant with Drs. Carmen Canavier, Chindo Hicks, Andrew Chapple and Kenneth Boe to purchase and deploy a cluster computer for the LSUHSC-NO campus to facilitate Bioinformatics and Biostatistics research (2018936).

In September 2019, Drs. Welsh and Taylor were awarded a Multi-PI R21 from NIH/NIAAA with Dr. Judd Shellito to study alcohol-induced dysbiosis and HIV associated pneumonia (1R21AA027199).

In April 2018, Vincent Maffei was awarded an F30 grant from NIH/NIAAA with Drs. Taylor and Welsh to study alcohol-associated intestinal dysbiosis and CD8+ T-cell activation and immunosenescence during HIV infection (1F30AA026527).

In August 2017, Dr. Taylor was awarded a Multi-PI R01 from NIH/NIAID with Drs. Alison Quayle and Ashok Aiyar to study the consequences of vaginal microbiota on clearance of Chlamydia in a cohort of subjects recruited from the New Orleans metro area (1R01AI118860).

In August 2017, Dr. Welsh was awarded a UH2 from NIH/NIAAA to study precision medicine approaches for alcohol and HIV-associated dysbiosis, immune activation, and cardiometabolic syndrome (1UH2AA026226).

In July 2016, Dr. Taylor was appointed as the Director of the Bioinformatics, Biostatistics, and Computational Biology Core of the Louisiana Biomedical Research Network. In this role he will lead the training and support of researchers throughout the Louisiana State University system in computational analysis of biomedical data.

In January 2015, Dr. Taylor was selected as the winner of $5,000 of Illumina sequencing regents in Illumina’s MiSeq My Focus contest. His entry described recent work in the MGRG exploring microbial diversity in the gastrointestinal tract, urogenital tract, airways and hospital environments. This research spotlight is featured on Illumina’s iCommunity newsletter portal.

Publications

Alcohol Use is Associated with Intestinal Dysbiosis and Dysfunctional CD8+ T-Cell Phenotypes in Persons Living with HIV

Maffei VJ, Siggins RW, Luo M, Brashear MM, Mercante DE, Taylor CM, Molina P, Welsh DA

PICRUSt2 for Prediction of Metagenome Functions

Douglas GM, Maffei VJ, Zaneveld JR, Yurgel SN, Brown JR, Taylor CM, Huttenhower C, Langille MG

Lifetime Alcohol Use Among Persons Living with HIV is Associated with Frailty

Maffei VJ, Ferguson TF, Brashear MM, Mercante DE, Theall KP, Siggins RW, Taylor CM, Molina P, Welsh DA

Antibiotic-modulated Microbiome Suppresses Lethal Inflammation and Prolongs Lifespan in Treg-deficient Mice.

He B, Liu Y, Hoang TK, Tian X, Taylor CM, Luo M, Tran DQ, Tatevian N, Rhoads JM

An Updated Conceptual Model on the Pathogenesis of Bacterial Vaginosis

Muzny CA, Taylor CM, Swords WE, Tamhane A, Chattopadhyay D, Cerca N, Schwebke JR

Lactobacillus reuteri DSM 17938 Feeding of Healthy Newborn Mice Regulates Immune Responses While Modulating Gut Microbiota and Boosting Beneficial Metabolites

Liu Y, Tian X, He B, Hoang TK, Taylor CM, Blanchard E, Freeborn J, Park S, Luo M, Couturier J, Tran DQ, Roos S, Wu G, Rhoads JM

Intestinal Microbial Products from Alcohol-fed Mice Contribute to Intestinal Permeability and Peripheral Immune Activation

Samuelson DR, Gu M, Shellito JE, Molina PE, Taylor CM, Luo M, Welsh DA

Lactobacillus reuteri Reduces the Severity of Experimental Autoimmune Encephalomyelitis in Mice by Modulating Gut Microbiota

He B, Hoang TK, Tian X, Taylor CM, Blanchard E, Luo M, Bhattacharjee MB, Freeborn J, Park S, Couturier J, Lindsey JW, Tran DQ, Rhoads JM, Liu Y

In Silico and Experimental Evaluation of Primer Sets for Species-Level Resolution of the Vaginal Microbiota Using 16S Ribosomal RNA Gene Sequencing

Van Der Pol WJ, Kumar R, Morrow CD, Blanchard EE, Taylor CM, Martin DH, Lefkowitz EJ, Muzny CA

Infant Colic Represents Gut Inflammation and Dysbiosis

Rhoads JM, Collins J, Fatheree NY, Hashmi SS, Taylor CM, Luo M, Hoang TK, Gleason WA, Van Arsdall MR, Navarro F, Liu Y

Alcohol Consumption Increases Susceptibility to Pneumococcal Pneumonia in a Humanized Murine HIV Model Mediated by Intestinal Dysbiosis

Samuelson DR, Siggins RW, Ruan S, Amedee AM, Sun J, Zhu QK, Marasco WA, Taylor CM, Luo M, Welsh DA, Shellito JE

Identification of Key Bacteria Involved in the Induction of Incident Bacterial Vaginosis: A Prospective Study

Muzny CA, Blanchard E, Taylor CM, Aaron KJ, Talluri R, Griswold ME, Redden DT, Luo M, Welsh DA, Van Der Pol WJ, Lefkowitz EJ, Martin DH, Schwebke JR

Deficiency of BrpA in Streptococcus mutans Reduces Virulence in Rat Caries Model

Wen ZT, Scott-Anne K, Liao S, De A, Luo M,, Kovacs C, Narvaez BS, Faustoferri R, Yu Q, Taylor CM, Quivey RG

CD Obesity-Prone Rats, but not Obesity-Resistant Rats, Robustly Ferment Resistant Starch Without Increased Weight or Fat Accretion

Obanda D, Page R, Guice J, Raggio AM, Husseneder C, Marx B, Stout RW, Welsh DA, Taylor CM, Luo M, Blanchard EE, Bendiks Z, Coulon D, Keenan MJ

The Respiratory Tract Microbial Biogeography in Alcohol Use Disorder

Samuelson DR, Burnham EL, Maffei VJ, Vandivier RW, Blanchard EE, Shellito JE, Luo M, Taylor CM, Welsh DA

Changes in the Gut Microbial Communities Following Addition of Walnuts to the Diet

Byerley LO, Samuelson D, Blanchard E 4th, Luo M, Lorenzen BN, Banks S, Ponder MA, Welsh DA, Taylor CM

Alcohol-Associated Intestinal Dysbiosis Impairs Pulmonary Host Defense Against Klebsiella Pneumoniae

Samuelson DR, Shellito JE, Maffei VJ, Tague ED, Campagna SR, Blanchard EE, Luo M, Taylor CM, Ronis MJJ, Molina PE, Welsh DA

Biological Aging And The Human Gut Microbiota

Maffei VJ, Kim S, Blanchard E 4th, Luo M, Jazwinski SM, Taylor CM, Welsh DA

Obese ZDF Rats Fermented Resistant Starch With Effects On Gut Microbiota But No Reduction In Abdominal Fat

Goldsmith F, Guice J, Page R, Welsh DA, Taylor CM, Blanchard EE, Luo M, Raggio AM, Stout RW, Carvajal-Aldaz D, Gaither A, Pelkman C, Ye J, Martin RJ, Geaghan J, Durham HA, Coulon D, Keenan MJ

Resetting Microbiota By Lactobacillus Reuteri Inhibits T Reg Deficiency-Induced Autoimmunity Via Adenosine A2A Receptors

He B, Hoang TK, Wang T, Ferris M, Taylor CM, Tian X, Luo M, Tran DQ, Zhou J, Tatevian N, Luo F, Molina JG, Blackburn MR, Gomez TH, Roos S, Rhoads JM, Liu Y